Journal of Data Mining in Genomics & Proteomics

John P Jakupciak

Publications

• Research Article
  Population Analysis of Bacterial Samples for Individual Identification in Forensics Application
  Author(s): John P Jakupciak, Jeffrey M Wells, Jeffrey S Lin and Andrew B FeldmanJohn P Jakupciak, Jeffrey M Wells, Jeffrey S Lin and Andrew B Feldman
  
  Biodefense preparedness begins with the ability to detect and respond to bio-threats, based on accurate interpretation of genetic information with sophisticated, yet easy-to-use bioinformatics tools. Microbial forensics further enables attribution of microbial pathogen samples back to a suspected source. Sample characterization and traceability back to source are dependent on genome identification of specific targets within samples, comprehensive analysis of mixtures of populations’ present, and detection of major/minor variations in the identified genomes and comparison of sample genetic profile against other samples. Commercial Next Generation Sequencing (NGS) platforms offer the promise of dramatically higher detection sensitivity and resolution of forensic DNA samples than is possible with methods in current use. Before applying these technologies for forensic analyses of ba.. View More»
  DOI: 10.4172/2153-0602.1000138

  Abstract PDF