Joanna Gasch

Joanna Gasch

Germany

Publications
  • Research Article
    Positively Charged Polyethersulfone Membranes: The Influence of Furosemide on the Zeta Potential

    Author(s): Joanna Gasch, Claudia S Leopold and Holger KnothJoanna Gasch, Claudia S Leopold and Holger Knoth

    The aim of the present work is to measure changes in the Zeta potential of uncharged (PES0) and positively charged (PES+) polyethersulfone membranes, and to investigate their chemical composition. Endotoxin-retentive filters with a 0.2 ?m PES0 and PES+ membranes are used for filtration of a furosemide sodium solution, with an increasing concentration up to 60 ?mol/l. To analyze the chemical composition of both membranes, X-Ray photoelectron spectroscopy (XPS) was used. The Zeta potential was determined by a streaming current electrokinetic analyzer. The positive charge of the PES+ membrane corresponding to a positive Zeta potential decreased with increasing furosemide sodium concentration. In contrast, the Zeta potential of PES0 membranes hardly changes with increasing drug concentration. XPS allows the determination of the chemical composition of the investigated membranes. Both membran.. View More»
    DOI: 10.4172/2155-9589.1000121

    Abstract