Jiqiu Qiao
China
Research Article
Dysglycemia and Dyslipidemia Models in Nonhuman Primates: Part II. Model of Naturally Occurring or Experimental Obesity
Author(s): Bingdi Wang, Guofeng Sun, Yongqiang Liu, Jiqiu Qiao, Weiwei Ye, Hui Wang, Xiaoli Wang, Keefe Chng, Wei Qiao, Yixin (Jim) Wang and Yong-Fu XiaoBingdi Wang, Guofeng Sun, Yongqiang Liu, Jiqiu Qiao, Weiwei Ye, Hui Wang, Xiaoli Wang, Keefe Chng, Wei Qiao, Yixin (Jim) Wang and Yong-Fu Xiao
Obesity is viewed as one of the most serious public health issues of this century, which is likely due to economic growth, urbanization, modernization, life-style change and decreased physical activity. In 2013, the American Medical Association classified obesity as a disease. Sustained excessive accumulation of body fat to the extent, such as overweight or obesity, can reduce life expectancy and increase health risks, particularly heart disease and type 2 diabetes. Cardiovascular, diabetes and other health problems of obesity have been studied for many decades. Inflammation, mitochondrial dysfunction, hyperinsulinemia, lipotoxicity, medical and others, such as genetic background and aging, may result in obesity. However, the underlying precise mechanisms have yet to be elucidated further. Various obesity animal models have been used and induced for o.. View More»
