Surgery: Current Research

Surgery: Current Research
Open Access

ISSN: 2161-1076


Jialiang Liang

Jialiang Liang


  • Review Article
    Stem/progenitor Cell Based Therapies for Repair of Myocardial Infarction: Current Developments in Methods of Cell Delivery
    Author(s): Jialiang Liang and Yigang WangJialiang Liang and Yigang Wang

    Regenerative medicine offers hope for patients with myocardial infarction (MI). A good deal of clinical evidence shows that the transplantation of stem/progenitor cells from numerous sources can produce significant protective effects in the injured heart, such as enhanced perfusion and contractility. The therapeutic effects of transplanted cells depend on appropriate delivery into the damaged area of the heart. Thus, the method of cell delivery is an important aspect of stem/progenitor cell based therapy, because it affects the fate of transplanted cells and consequently determines the clinical outcome. It is still difficult to determine the optimal cell delivery strategy for MI treatment from the current preclinical and clinical studies, although cell injections have been widely used in the delivery of various types of progenitor cells in clinical trials. Additionally, cell patch eng.. Read More»
    DOI: 10.4172/2161-1076.1000131

    Abstract PDF

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