Journal of Data Mining in Genomics & Proteomics

Jeffrey Zheng

Publications

• Research Article
  Variant Map Construction to Detect Symmetric Properties of Genomes on 2D Distributions
  Author(s): Jeffrey Zheng, Weiqiong Zhang, Jin Luo, Wei Zhou and Veronica LiesaputraJeffrey Zheng, Weiqiong Zhang, Jin Luo, Wei Zhou and Veronica Liesaputra
  
  Visualization Methods have played a key role in the Human Genome Project. After further development in other international projects such as ENCODE, larger numbers of Genome Databases are established and mass Genomewide gene expression measurements are developed. In current situation, it is necessary to shift targets in computational cell biology from collecting sequential data to making higher-level interpretation and exploring efficient content-based retrieval mechanism for genomes. Mammalian genomes encode thousands of large non-coding RNAs (lncRNAs), many of which regulate gene expression, interact with chromatin regulatory complexes, and are thought to play a role in localizing these complexes to target loci across the genome. Using higher dimensional visualization tools, their complex interactive properties could be organized as different visual maps. The Variant Map Construction.. View More»
  DOI: 10.4172/2153-0602.1000150

  Abstract PDF