Journal of Vaccines & Vaccination

Journal of Vaccines & Vaccination
Open Access

ISSN: 2157-7560

Jane Megid

Jane Megid
Faculty of Veterinary Medicine,

  • Review Article
    Vaccinia Virus: It’s Use in Smallpox Vaccine and Epidemiology
    Author(s): Jane MegidJane Megid

    Vaccinia Virus (VACV) was widely used in smallpox vaccines in Brazil during the world vaccination campaign of Word Health Organization. After ends of this campaign in Brazil in 1980, zoonotic Vaccinia outbreaks have been recorded in several regions of the country. Researches believed that the VACV used in the word vaccination campaign in Brazil was involved in the re-emergence of the disease. To analyze the similarity between the viruses isolated from outbreaks and those used during Smallpox eradication, phylogenetic analyzes of vaccines viruses were compared to VACV isolated in outbreaks, and the result obtained was that Brazilians VACV are not grouped with vaccines viruses. The origin of outbreaks remains unknown in Brazil, but the most accepted theory assumes that there is populations of VACV genetically diverse circulating in still unknown natural reservoirs, and according on biol.. Read More»
    DOI: 10.4172/2157-7560.1000261

    Abstract PDF

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