Jagnani VK
Agrasen Hridayalaya Research Foundation,
Ranchi, Jharkhand
India
Research
Effect of Hydroxychloroquine on Type 2 Diabetes Mellitus Unresponsive to More Than Two Oral Antidiabetic Agents
Author(s): Jagnani VK, Bhattacharya NR, Satpathy SC, Hasda GC and Sourav ChakrabortyJagnani VK, Bhattacharya NR, Satpathy SC, Hasda GC and Sourav Chakraborty
Background and aims: The aims of the present study were to evaluate the effectiveness of Hydroxychloroquine as an add-on therapy to metformin and Sulfonylurea (SU) in reducing glycosylated hemoglobin (HbA1c) to achieve therapeutic goals. Methods: In this open-labelled comparative observational study, two groups of 100 uncontrolled Type 2 Diabetes Mellitus (T2DM) patients in each were studied for 24 Weeks (6 months). Both the groups were divided into patients who were on triple drug combinations. One group receiving Metformin,Glimepiride and Tenelegliptin and the other group received Metformin,Glimepiride and Hydroxychloroquine. In each group fasting blood sugar and as postprandial blood sugar were tested at the start of the study and at 4 weeks intervals. HbA1c was tested at the beginning of study, at 12 Weeks (3 months) and at the end of 24 weeks (6 months). Results: After 24 weeks o.. View More»
