Go J Yoshida

Go J Yoshida
Division of Gene Regulation, Institute for Advanced Medical Research, School of Medicine,
35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582
Japan

Publications
  • Review Article
    The Novel Anti-tumor Therapy Targeting the “Functional” Cancer Stem Cell Markers
    Author(s): Go J Yoshida and Hideyuki SayaGo J Yoshida and Hideyuki Saya

    It has recently been reported that molecular targeting drugs fail to overcome the ?oncogene/oncogenic signaladdiction? of cancer cells. Tumor tissue is composed of heterogeneous cancer cells, so that the therapeutic response is difficult to predict. Recent advance in cancer research has strongly suggests that cancer stem cells contribute to the formation and maintenance of the heterogeneous cellular society in the tumor tissue. After all, this heterogeneity is the major cause of the acquired resistance to anti-tumor therapies. In this commentary, we would like to briefly explain the promising therapeutic targets of CD44 variant isoform and EpCAM, the ?functional? cancer stem cell markers. .. View More»
    DOI: 10.4172/2161-1459.1000147

    Abstract PDF