Entesar Ali Saber
Egypt
Research Article
Effect of Quercetin on the Endocrine Pancreas of the Experimentally Induced Diabetes in Male Albino Rats: A Histological and Immunohistochemical Study
Author(s): Rehab Ahmed Rifaai, Nashwa Fathy El-Tahawy, Entesar Ali Saber and Randa AhmedRehab Ahmed Rifaai, Nashwa Fathy El-Tahawy, Entesar Ali Saber and Randa Ahmed
Background: Insulin dependent diabetes mellitus is a chronic metabolic disease. Many drugs used in its treatment which have a number of serious adverse effects. Natural agent as quercetin (QCT) has been suggested in the alternative medicine for treatment of diabetes mellitus.
Aim of the work: To evaluate the effect of QCT on the histological changes which occur in the islet of Langerhans of the streptozotocin (STZ)-induced diabetic rats and the possible mechanisms through which QCT produces its protective effect.
Materials and methods: Fourty five male albino rats were divided into 3 groups: Group I, control group; 15 rats received single intraperitoneal injection of citrate buffer saline. Group II, diabetic group; 15 rats received single intraperitoneal injection of STZ. Group.. View More»
