Clinical Microbiology: Open Access

Emel Uzunoglu

Publications

• Research Article
  Determination of Piperacillin/Tazobactam and Ticarcillin/Clavulanate Susceptibilities in Pseudomonas aeruginosa Isolates in Hospitalised Patients by E-test Gradient Method and Comparison of Results with Disk Diffusion Tests
  Author(s): Şahin Direkel, Emel Uzunoglu, Çağla Uzalp, Ezgi Findik, Said Tontak and Cengiz AhmadliŞahin Direkel, Emel Uzunoglu, Çağla Uzalp, Ezgi Findik, Said Tontak and Cengiz Ahmadli
  
  Pseudomonas aeruginosa is an important opportunistic pathogen in human infections. P. aeruginosa is naturally resistant to many antibiotics and mutations can result in resistance development during treatment as well. Piperacillin/tazobactam and Ticarcillin/clavulanate are β-lactam/β-lactamase inhibitor combination with a wide spectrum of antibacterial activity. In this study was aimed to determine the susceptibility of P. aeruginosa isolates to Piperacillin/tazobactam and Ticarcillin/clavulanate antibiotics by Epsilometer test in the patients in intensive care units of Giresun State Hospital and to compare PIP/TZP results by Disk Diffusion method. Sensitivities of PIP/TZP were determined via Kirby Bauer disk diffusion method and MIC values of the isolates against PIP/TZP and TIC/CLA were determined by E-test. By using E-test method and in accordance with the CLSI standards, .. View More»
  DOI: 10.4172/2327-5073.1000273

  Abstract PDF