Doss A

Doss A
National College (Autonomous),
Tiruchirappalli-60001, Tamil Nadu
India

Publications
  • Research Article
    Free Radical Scavenging Activity of Solanum trilobatum Linn. on Alloxan -Induced Diabetic Rats
    Author(s): Doss A and SP AnandDoss A and SP Anand

    Solanum trilobatum is reported to have a wide range of biological activities such as antidiabetic, antibacterial, antifungal, antimitotic, antioxidant, antitumours and is used for treatment of asthma, to arrest blood vomiting and several kinds of leprosy. In the present study, we report the effect of ethanol extracts of S.trilobatum leaf on free radical scavenging activity, in alloxan induced diabetic rats. The lipid peroxidation, superoxide dismutase and catalase were measured in liver homogenate, and Serum Glutamic Pyruvic Transaminase (SGPT), Serum Glutamic Oxaloacetic Transaminase (SGOT), cholesterol and glucose were measured in blood serum. Oral administration of single dose of alloxan monohydrate (1mg/kg), caused significant increases in Lipid Peroxidation (LPO), SGOT, SGPT and glucose levels, while Superoxide Dismutase (SOD) and Catalase (CAT) levels were significantly decrease.. View More»
    DOI: 10.4172/2161-1009.1000115

    Abstract PDF