Don McClellan
Tanzania
Research Article
Is A1C Less Concordant with OGTT in Children as Compared in Adults? Data from a Hispanic Community in Arizona
Author(s): Maria Corazon Hizon, Chirag Kapadia, Pamela Garcia-Filion, Don McClellan and Gabriel ShaibiMaria Corazon Hizon, Chirag Kapadia, Pamela Garcia-Filion, Don McClellan and Gabriel Shaibi
Early efforts to identify hyperglycemia and those at risk for developing type 2 diabetes (T2DM) are warranted. For decades, the diagnosis of T2DM has been based on plasma glucose (PG) criteria but recent recommendations include the use of A1C for identifying hyperglycemia. These recommendations are based upon adult studies and data suggests that A1C may be less concordant in children, as compared to adults. The purpose of our study was to compare A1C, fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) between adolescents and adults in Hispanic population at disproportionate risk for developing T2DM. Methods: Data from self-identified as Latino, 91 overweight adolescents, and 406 overweight adults were assessed after an overnight fast for A1C, FPG and OGTT results. Receiver Operator Characteristics Curves for A1C vs. any hyperglycemia (prediabetes or diabetes) were the.. View More»
