Journal of Liver

Journal of Liver
Open Access

ISSN: 2167-0889


Denitsa Dukova

Denitsa Dukova
Clinic of Hepatogastroenterology, University Hospital “Saint Marina” -Varna. 1,
Hristo Smirnenski Str. 9010 Varna

  • Research Article
    Clinical Analysis of 75 Patients with Primary Biliary Cirrhosis
    Author(s): Denitsa Dukova and Iskren KotzevDenitsa Dukova and Iskren Kotzev

    Background and aims: Primary biliary cirrhosis is a chronic and slowly progressive cholestatic liver disease characterized by destruction of interlobular bile ducts, which if untreated, leads to fibrosis, cirrhosis and liver failure. It is more frequent among female patients and is usually diagnosed in the fifth decade of life. This study aims to determine the demographic, clinical, biochemical and serological characteristics and histological stage of patients with primary biliary cirrhosis. Methods: Retrospective analysis of the adult patients diagnosed with primary biliary cirrhosis at our center from January 2005 to December 2013 was performed. Data collection included demographics, clinical features, biochemical and serological markers, and histological stage. Results: 75 patients were diagnosed with primary biliary cirrhosis (mean age: 55 years, range: 19-83), of whom 92.0% were .. Read More»
    DOI: 10.4172/2167-0889.1000161

    Abstract PDF

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