Hereditary Genetics: Current Research

Hereditary Genetics: Current Research
Open Access

ISSN: 2161-1041


Clement ND

Clement ND
Speciality Trainee Trauma and Orthopaedics, Royal Infirmary of Edinburgh,
Little France, EH16 4SA

  • Review Article
    Is Osteoarthritis of the Knee Hereditary? A Review of the Literature
    Author(s): Clement NDClement ND

    Osteoarthritis (OA) of the knee joint is a common cause of disability. This review presents the current evidence and knowledge regarding the genetic inheritability of OA of the knee, and a contemporary hypothesis for progression of the disease. The current evidence would suggest there is a hereditary predisposition to OA of the knee. However, this would seem to be multifactorial and the development of OA in the knee may depend upon multiple genetic factors, not only of those relating to cartilage degeneration but also of those relating to the morphology of the knee joint, both of these factors seem to be influenced by similar genes. Knowledge of these genes that affect the initiation and/ or progression of knee OA are important for development of new treatment options at an early stage of the disease preventing future physical disability... Read More»
    DOI: 10.4172/2161-1041.S1-004

    Abstract PDF

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