Chaffai Haifa
Tunisia
Research Article
Hemolytic Uremic Syndrome Complicating Invasive Streptococcus pneumoniae
Infections: Tunisian Experience
Author(s): Hammi Yousra, Sayari Taha, Chaffai Haifa, Borgi Aida, Jallouli Manel, Abidi Kamel, Bouziri Asma, Khaldi Ammar, Ben Jaballah Najla and Gargah TaharHammi Yousra, Sayari Taha, Chaffai Haifa, Borgi Aida, Jallouli Manel, Abidi Kamel, Bouziri Asma, Khaldi Ammar, Ben Jaballah Najla and Gargah Tahar
Hemolytic uremic syndrome (HUS), characterized by the triad of micro-angiopathic hemolytic anemia, thrombocytopenia, and acute renal insufficiency, is a common cause of acute renal failure in children. It usually follows an episode ofgastroenteritis with enterotoxigenic Escherichia coli and is termed typical HUS. However, HUS is also a complication of invasive pneumococcal infection. Reasons for not diagnosing this condition include the absence of a specific laboratory test, the lack of consistent case definitions, unfamiliarity, a misdiagnosis of disseminated intravascular coagulation (DIC), and cases with micro-angiopathic hemolytic anemia and only mild renal injury. The aim of our study is to describe the epidemiology, the treatment and the evolution of HUS after invasive pneumococcal infections in Tunisia. Cases were identified be.. View More»
