Boerwinkle E

Boerwinkle E

Tanzania

Publications
  • Research Article
    Causal Inference in the Age of Decision Medicine
    Author(s): Yazdani A and Boerwinkle EYazdani A and Boerwinkle E

    Causal analyses and causal inference is a growing area of biostatics. In parallel, there is increasing focus on using genomic information to guide medical practice, i.e. personalized medicine or decision medicine. This perspective discusses causal inference in the context of personalized or decision medicine, including the assumptions and the concept that the task is different depending on whether the primary goal is the average response of treatment in the population or the ability to characterize the response for an individual or a subgroup. This perspective provides a tutorial of modern causal inference and then provides suggestions how application of specific kinds of causal inference would promote advances in translational sciences. The concept of the subpopulation causal effect is one path toward improved decision medicine. A dataset containing cardiovascular disease risk factor.. View More»
    DOI: 10.4172/2153-0602.1000163

    Abstract PDF