Attiya Sabeen Rahman
Karachi Medical and Dental College and Abbasi Shaheed Hospital,
Karachi
Pakistan
Research Article
Sub-Clinical Thyroid Disorders in Patients With Hepatitis C Before and After Conventional Treatment
Author(s): Attiya Sabeen Rahman, Muhammad Amir, Adnan Aziz, Muhammad A Siddiqui, Qaiser Jamal and Mehwish RiazAttiya Sabeen Rahman, Muhammad Amir, Adnan Aziz, Muhammad A Siddiqui, Qaiser Jamal and Mehwish Riaz
Objective: Thyroid dysfunction represents one of the commonest endocrine manifestations of chronic hepatitis C infection, exaggerated by interferon based treatment. The purpose of this study was to assess the frequency of hepatitis C virus and sub-clinical thyroid disorder in patients with hepatitis C before and after treatment.
Methods: This is an observational, cross sectional analysis conducted in Lyari general hospital and Abbasi Shaheed hospital from January 2009 to December 2015. Patients with a positive rt-PCR and genotype 3 were included in the study. After a positive rt-PCR, patients were screened by thyroid stimulating hormone before starting the treatment. All patients were given therapy of conventional interferons (3 million units thrice weekly) and ribavirin (800 mg per day in two divided doses) for a period of 6 months. Patient.. View More»
