Asia Naz

Asia Naz

Pakistan

Publications
  • Research Article
    Synthesis Characterization and Antimicrobial Activities of Azithromycin Metal Complexes
    Author(s): Saeed Arayne M, Najma Sultana, Sana Shamim and Asia NazSaeed Arayne M, Najma Sultana, Sana Shamim and Asia Naz

    Azithromycin is a well-established antimicrobial agent which has been widely prescribed for the treatment of respiratory tract infections owing to its high efficacy and safety. Various essential metal complexes of azithromycin were synthesized and characterized by techniques as UV, FT-IR, NMR, atomic absorption and elemental analysis. Spectroscopic studies of complexes suggested that the –N(CH3)2 and hydroxyl group of desosamine sugar moiety present in azithromycin has been involved in complexation i.e., azithromycin ligand (L) behaves bidentately for complexation with different metal ions such as Mg (II), Ca (II), Cr (III), Mn (II), Fe (III), Co (II), Ni (II), Cu (II), Zn (II) and Cd (II). These complexes were then subjected to in-vitro antibacterial and antifungal studies against several Gram positive, Gram negative bacteria and fungi. ANOVA studies illustrates that all the te.. View More»
    DOI: 10.4172/2329-6798.1000133

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