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Arif Mand Sohail Afzal M
Arif Mand Sohail Afzal M
School of Science,
Lahore
Pakistan
Publications
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Review Article
Antibiotic Resistance Pattern of Escherichia coli and Klebsiella Species in Pakistan: A Brief Overview
Author(s): Arif Mand Sohail Afzal MArif Mand Sohail Afzal M
Antibiotics kill or inhibit the replication of bacteria by different means, like emergence of resistance to these antibiotics is serious threat to health care system across the globe. Pathogens can attain drug resistance either by intrinsic mechanism or may be acquired due to selective pressure of a drug. Escherichia coli (E. coli) and Klebsiella specie (K. species) are the most common causative pathogens for most of the infections especially in countries with poor health care systems. Increase in extended-spectrum β-lactamases (ESBL) production in these microbes in recent years has led to limitations of treatment. Pakistan is also one of these countries with very low budget for health and per capta income. In Pakistan, majority of health care professionals prescribe antibiotic without testing the pathogen for antibiotic susceptibility. Long term utilization of antibioti.. View More»
DOI: 10.4172/1948-5948.1000377