Journal of Blood Disorders & Transfusion

Alfatih Aboalbasher Yousif

Publications

• Research Article
  The Role of Factor V Leiden 1691G>A and Prothrombin Gene 20210G>A Mutations in Hypercoagulable State Associated with Venous Thromboembolism among Sudanese Patients
  Author(s): Alfatih Aboalbasher Yousif, Abdel Rahim Mahmmoud Muddathir, Elwaleed Mohamed Elamin and Ahmed AlhadiAlfatih Aboalbasher Yousif, Abdel Rahim Mahmmoud Muddathir, Elwaleed Mohamed Elamin and Ahmed Alhadi
  
  Background: Factor V Leiden (FVL) 1691G>A and Prothrombin (PRT) 20210G>A mutations are the most frequent hereditary cause of venous thrombosis in Caucasian and less frequency in African. The aim of this study was to detect the frequency of FVL 1691G>A and PRT 20210G>A mutations among Sudanese venous thromboembolism (VTE) patients. Material and Methods: This was descriptive Cross sectional study in which a total of 176 Sudanese subjects were enrolled in the period between July 2015 and July 2016. Among them, 38 apparently healthy Sudanese individuals as controls and 138 patients (47 males and 91 females), age range 18-90 with documented VTE confirmed by Duplex Doppler ultrasound at Khartoum Teaching Hospital and Sudan Heart Institute were included. Result: In this study, the mean age was 48 years and 67% of total VTE patients were over the age of 40 years. Increased age was.. View More»
  DOI: 10.4172/2155-9864.1000386

  Abstract PDF