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Digital health technologies have emerged as transformative tools within pharmacy practice, playing a pivotal role in reshaping medication management and enhancing patient outcomes. The integration of telepharmacy, Artificial Intelligence (AI), blockchain, mobile health applications, and Electronic Health Records (EHRs) has provided innovative solutions to longstanding inefficiencies in traditional pharmacy systems. These technologies enable improved medication adherence, enhanced patient safety, and broadened access to care while facilitating personalized and efficient service delivery. However, challenges persist, including those related to data privacy, regulatory compliance, digital literacy, and financial constraints. This review examines the evolving role of digital health technologies in pharmacy, critically evaluates their impact on medication management and patient outcomes, and identifies future directions for their effective and sustainable implementation.