Brain Disorders & Therapy

Abstract

Tyrosine Kinase and Mitogen Activated Protein (MAP) Kinase Pathway on Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage

Flavio Ramalho Romero and Marco Antônio Zanini

Cerebral vasospasm is a severe complication after an aneurysm rupture. Many efforts have been done to understand the complexity signaling pathways involved in this condition. MAP kinase has been suggested to be one of the most important signaling pathways involved in cerebral vasospasm. This pathway is clinically important as it has both outcome and therapeutic implications.