Daily exposure to the stressor whether distress or eustress increase production of some hormones such as epinephrine, norepinephrine, cortisol, dopamine and serotonin and other. A group of them mainly function as excitatory and other function as inhibitory. However, the body reacts differently to distress and eustress while both secrete the same hormones. in case of flight to flight action that occur during distress, the interaction of these hormones enhances the body to be more focus on the surrounding environment, by stimulating senses memory, sight, hearing and other senses become sharper, however, long exposure to these hormones is dangerous on the heath. This body response should help to overcome adversity, whereas the body has different response it can be a positive or negative reaction, dealing with stress can be difficult, mindset and lifestyle have an enormous impact on stress which can help to adapt to stress reaction and utilization the hormonal interaction to get positive performance.