Modern Chemistry & Applications

Abstract

Synthesis, Characterization and Biological Approach of N’-(3-(Hydroxy Imino) Butan-2-ylidene)-2-Oxo-2H-Chromene-3-Carbohydrazide Complexes.

Zaky RR, Ibrahim KM and Abouelala EE

A series of metal complexes of Cu(?), Co(?), Ni (?), Cd(?) and Hg(?) complexes with N’-(3-(hydroxyimino) butan- 2-ylidene)-2-oxo-2H-chromene-3-carbohydrazide (H₂L) were prepared. The structures illuminated by elemental and thermal analysis, besides spectroscopic methods (IR, ¹H NMR, and UV-visible, MS) and physical measurements (molar conductance and magnetic susceptibility). In addition, DFT method used to approve the geometry of solid complexes. From conductmetric measurements, all complexes were non-electrolytic and formed by molar ratio 1:2 expect Hg(?) complexes by 1:1. Moreover, the biological activity (Antibacterial, antifungal and DNA binding) performed for all prepared compounds.