Abstract

Rethinking the Bacterial Genetic Regulation

Sylvie Reverchon, Patrick Sobetzko, William Nasser and Georgi Muskhelishvili

Bacteria are the most ancient and abundant organisms on the earth. Whereas bacterial organisms served as first cellular model systems for explorations of genetic control by approaches of molecular biology, our understanding of bacterial gene regulatory mechanisms is still far from complete. Yet, deep insights into genetic regulation are urgently required due to the increased frequency of nosocomial infections caused by multidrug-resistant bacteria, as well as increased agricultural damage caused by the bacterial plant pathogens.