As the human population doubles every few decades, so its impact on the environment increases at a faster rate. Humans cannot escape the decree of population growth; when population increases, the resources required for its sustenance also increases, therefore human has made a remarkable impact on the environment primarily through the use of natural resources and production of wastes. This paper examines the impact of population growth in one of frontier states of north-east India, i.e. Arunachal Pradesh on the environment and the attendant result on human health. Rapid growth of human population has been identified as underlying environmental problems in the state. The paper recommends measures to limit rapidly growing population as well as strategies to reduce the negative impact of human activities on the environment.