This review aims to provide a literature survey on how the Natural Antioxidants. Continuous exposure of the skin to oxidative stresses leads to the formation of the reactive oxygen species with in body, skin and cell of the host organism. The accumulation of these reactive species can result in the damage to cellular DNA and cell membrane lipids and proteins. Damage to these organelles produces free radicals that start a vicious cycle that can lead to increase cell damage and senescence. To overcome this problem, our skin contains the cutaneous antioxidants, but it soon gets depleted on exposure to UV rays and also because of environmental stresses. The overload of these oxidative stresses will lead to chronic and degenerative diseases like cancer, autoimmune disorder, aging, cataract, rheumatoid arthritis, cardiovascular and neurodegenerative diseases. These antioxidants have to be replenished to overcome these oxidative stresses. Therefore the use of natural antioxidants is a promising strategy to with respect to oxidation of cells.