A study was undertaken at TNAU, Coimbatore to envisage the effect of different chemicals and growth regulators in combination with Thiabendazole (Fungicide) on post-harvest quality and shelf life of banana cv. Nendran (French Plantain Musa AAB). Various concentration of, GA3, BA, CaCl2 and Hot water treatment either alone or in combination with Thiabendazole was applied to fruits after harvest to study their impact on post-harvest quality and shelf life. Exogenous application of chemicals, growth regulators in combination with Thiabendazole significantly decreased post-harvest disease incidence leading to increase in post- harvest fruit quality and shelf life. Among the treatments, post-harvest dipping of fruits in 150 ppm GA3 + 200 ppm Thiabendazole significantly increased firmness (3.70 kg/cm2) titrable acidity (0.09%) and storage life of fruits (18.00 days). While the parameters like PLW (13.53%), TSS (25.45oB), total sugars (18.88%), reducing sugars (17.11%) and percent disease incidence (5.55) was observed minimum in the same treatment after 12th day of storage.