Abstract

Impact of Deep Brain Stimulation Therapy on Autonomic Disturbances and Related Symptoms of Parkinson's Disease

Xiang Hong Wang, Laura Sperry, John Olichney, Sarah Tomaszewski Farias, Kiarash Shahlaie, Norika Malhado-Chang, Vicki Wheelock and Lin Zhang

Deep brain stimulation (DBS) is an effective treatment option for patients with Parkinson’s disease (PD), essential tremor and certain types of dystonia. DBS surgery is typically offered to patients that have diminishing benefits from dopamine replacement therapy with prominent motor fluctuations. Recent research has also shown that DBS can have a significant impact on non-motor symptoms (NMSs), including influencing autonomic and related symptoms. In this editorial, we will evaluate these publications and discuss the often positive impact of DBS on autonomic symptoms, weight changes, sleep disturbances and sensory function.