Journal of Vaccines & Vaccination

Abstract

Evolution of the Residual Risk of Transmitting HIV, HCV and HBV in the Blood Transfusion from 1998 to 2009 in Cote d’Ivoire

Adeoti FM, Oyourou AO, Sirancy- Bogui L, Konate S and Sess ED

Prevention of viral contamination of blood from blood bags collected remains a concern finds strategies traceability of blood products and blood safety in Côte d’Ivoire. Thus, the authors have estimated the residual risk of transmission of human immunodeficiency virus (HIV), Hepatitis B virus (HBV) and Hepatitis C (HCV) among blood donors in four periods of three years, 1998-2000, 2001-2003, 2004-2006, 2007-2009 from data collected at the blood establishments in the national territory.

The determination of HIV antibodies against the hepatitis C virus and the surface antigen of hepatitis B (HBsAg) were carried out by immuno-enzymatic techniques plate (ELISA) associated with the residual risk assessment.

The results showed a gradual decrease of the residual risk of HIV to be the lowest in the period 2007-2009 with 12 per 100 000 or 1 per 8333 donations. Residual risk of hepatitis B and C have known an increase during the different periods to be respectively 219 to 100 000 or 1 457 and 1180 per 100 000 or 1 per 85 donations over the period 2007-2009.

The residual risk of HCV is 98 times higher than HIV and 18 times that of hepatitis B. These results show that efforts must be continued in the steps of donor selection, confirmation of screening test for viral contamination and assessment of residual risk of viral transmission during blood transfusion