Biology and Medicine

Abstract

Effects of gonadectomy and steroid administration on histomorphometric properties of heart in male rabbit

*Fatahian Dehkordi RA, Parchami A

The aim of the present study was to investigate effects of testosterone propionate (TP) on the histological properties of heart in gonadectomized rabbits. Fifteen New Zealand white rabbits, 2.5-month-old, were selected in this study. The animals were divided into 3 operation groups: sham-operated control animals (Co), gonadectomy animals (Go) and testosterone administration (TA). Gonadectomized rabbit hearts were compared with hearts of sham-operated control animals and their testosterone induction. Heart diameter and length of left and right epicardium in gonadectomized animals do not have any statistically significant difference than sham-operated rabbits. Heart weight, right and left ventricle thickness, and right and left cardiac myocardium decreased statically in gonadectomized animals as compared to the control group and increased significantly (p