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Abstract

Development of Affordable Effective Vaccines against Whooping Cough for the Developing World

Trilochan Mukkur and Peter Richmond

The rate of mortality in children associated with serious infectious diseases is significantly higher in the developing world and in socioeconomically disadvantaged populations in developed industrialized countries. The reasons underpinning the higher incidence of whooping cough (pertussis) in these populations include overcrowding and poor hygiene, poor coverage with available pertussis containing vaccines and waning immunity following immunisation and infection.