AK Al-Miraj* and Md. Iktier Hassan Khan
Diabetes Mellitus is a metabolic disorder characterized by hyperglycemia and associated disturbances in carbohydrate, fat and protein metabolism because of absolute or relative insulin deficiency. Excess iron damages β-cells of pancreas due to oxidative stress contributing to pathogenesis of diabetes mellitus. Diabetes is a metabolic disorder characterized by hyper glycaemia & raised HbA1c. Serum Ferritin is an acute phase protein and it is a marker of iron stores in the body. The aim of this study is to establish a correlation between serum ferritin and glycated hemoglobin levels in type 2 diabetes mellitus patients. This study was done in the department of Medicine, Tertiary-level hospital, Dhaka, Bangladesh done from July-2019 to Jun-2020. The study comprised of total 100 subjects. Blood samples were analyzed for Ferritin, HBA1c and fasting plasma glucose. Serum ferritin was significantly higher in diabetic patients when compared with control group (p<0.001). Serum ferritin is positively correlated with HbA1c and also serum ferritin had a positive correlation with increasing duration of diabetes. Serum ferritin and HBA1c level were elevated in patients with type 2 diabetes mellitus when compared to healthy individuals and it indicates that serum ferritin can be used as a marker for glycemic control in diabetic patients.
