Bloodstream Infection in the Paediatric Cancer Patients: Bacteriological Profile and Drug Resistance Patterns in Shenzhen, China

Bloodstream Infections (BSI) remain a main cause of death in pediatric cancer patients. We present the first report on the microbiological profile of bacteremia and drug resistance patterns in Shenzhen, China. We examined the types of bloodstream infectious agents and their antimicrobial susceptibility pattern in the pediatric oncology patients, from Shenzhen Children’s Hospital from January 2016 to October 2018. Acinetobacter baumannii (12.82%), Klebsiella pneumoniae (12.82%) and Staphylococcus epidermidis (34.61%) were highly prevalent in cancer patients with bloodstream infection. Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae were also predominant. 29% of isolates were resistant to more than two class of antibiotics so call them as multi-drug resistant isolates.